Found 13 matching trials
A Phase II, Multi-Center, Open-Label, Uncontrolled Study to Evaluate the Efficacy and Safety of Sorafenib Given Daily in Combination With Repeated 21-Day Cycles of Dacarbazine (DTIC) Chemotherapy in Subjects With Advanced Metastatic Melanoma PHASE2 The purpose of this study is to see whether a new type of anti-cancer drug,...
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Multiple Locations
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Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable Melanoma PHASE2 RATIONALE: Drugs used in chemotherapy, such as temozolomide, work in differ...
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Abramson Cancer Center of the University of Pennsylvania
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Radiation Therapy and Temozolomide Followed by Temozolomide Plus Sorafenib for Glioblastoma Multiforme PHASE2 The mechanism of action of sorafenib makes it an interesting drug to invest...
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Florida Cancer Specialists
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Sorafenib and Temozolomide in Treating Patients With Stage III or Stage IV Melanoma PHASE1 RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of...
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Institut Gustave Roussy
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Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors PHASE2 This protocol will study treatment for Ewing sarcoma family of tumors (ESFT...
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St. Jude Children's Research Hospital
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Treatment for Subjects With Unresectable Stage III or Stage IV Melanoma PHASE2 This is a randomized, double blind, placebo controlled, multicenter, phase ...
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Multiple Locations
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Phase II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma PHASE2 The goal of this clinical research study is to find the highest tolerable d...
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Multiple Locations
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Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma PHASE1 The goal of this clinical research study is to find the highest tolerable d...
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University of Texas MD Anderson Cancer Center
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Sorafenib and Dacarbazine in Soft Tissue Sarcoma PHASE2 The purpose of this study is to find out what effects, good and/or bad, the...
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Memorial Sloan-Kettering Cancer Center
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Monocentric Pilot Study Investigating the Metabolic Activity of Melanoma in Vivo During Sorafenib and Dacarbazine PHASE2 Investigation of the metabolic activity of sorafenib and sorafenib plus dac...
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Department of Dermatology, University Hospital Zurich
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